At Neurocrine Biosciences, we pride ourselves on having a strong, inclusive, and positive culture based on our shared purpose and values. We know what it takes to be great, and we are as passionate about our people as we are about our purpose - to relieve suffering for people with great needs, but few options.
What We Do:Neurocrine Biosciences is a neuroscience-focused, biopharmaceutical company with a simple purpose: to relieve suffering for people with great needs, but few options. We are dedicated to discovering and developing life-changing treatments for patients with under-addressed neurological, endocrine and psychiatric disorders. The company's diverse portfolio includes FDA-approved treatments for tardive dyskinesia, Parkinson's disease, endometriosis* and uterine fibroids*, as well as clinical programs in multiple therapeutic areas. For three decades, we have applied our unique insight into neuroscience and the interconnections between brain and body systems to treat complex conditions. We relentlessly pursue medicines to ease the burden of debilitating diseases and disorders, because you deserve brave science. *in collaboration with AbbVie
About the Role:Responsible for assigned small molecule purification and analysis studies, in support of discovery programs at Neurocrine Biosciences Inc. using, but not limited to, HPLC and SFC chromatography, method development/optimization, achiral and chiral small molecule analysis and purification, and instrument maintenance/ troubleshooting.
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Your Contributions (include, but are not limited to):Performs daily achiral small molecule analyses and purifications in a high throughput setting utilizing both LC and SFC instrumentation
Executes and/or optimizes HPLC/SFC methods for achiral/chiral small molecules; supports the development of chiral and achiral methodologies to purify small molecules using mass-directed HPLC and SFC technology
Perform routine instrument maintenance, repair and may troubleshoot complex instrument issues
Operates liquid handling robotics
Uses sample data to develop preliminary analysis and findings
Support the development of presentations of laboratory studies/analysis and findings
Regularly sets up laboratory for new and/or continued purification and analysis
Other duties as assigned
Bachelor's degree in Chemistry, Biochemistry or similar discipline and 2+ years of experience in pharmaceutical industry, specifically small molecule purification and analysis. Hands-on experiences with HPLC / SFC Chromatography and liquid robotics preferred. Experience with analytical method development and preparative chromatography for small molecule chiral and achiral pharmaceutical compounds. Experience in instrument maintenance and troubleshooting preferred OR
MS degree in Chemistry, Biochemistry or similar discipline and some industry experience as noted above OR
PhD degree in Chemistry, Biochemistry or similar discipline and some industry or relevant experience a plus
Ability to identify complex problems and solves routine problems
Ability to work under various timelines, while maintaining quality of work
Working knowledge of HPLC/SFC chromatography. Analytical and preparative focus with this technology is required
Continuous drive to increase lab productivity and throughput through scientific creativity
Recognizes fundamental anomalies in data points and identifies issues in experiments / processes
Begins to understand how to think outside of the technical process and consider the impact decisions will have on the broader scientific goals
Strong knowledge of one scientific discipline
Good knowledge of scientific principles, methods and techniques
Good knowledge and demonstrated ability working with a variety of laboratory equipment/tools
Ability to work as part of a team Strong computer skills
Good problem-solving, analytical thinking skills
Detail oriented
Ability to meet deadlines
Good project management skills
Strong communication skills, ability to work independently, and creative approaches to problem solve, are essential in performing daily tasks and responsibilities
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Neurocrine Biosciences is an EEO/AA/Disability/Vets employer.
We are committed to building a diverse, equitable, and inclusive workplace, and we recognize there are a variety of ways to meet our requirements. We are looking for the best candidate for the job and encourage you to apply even if your experience or qualifications don't line up to exactly what we have outlined in the job description.
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